New York, USA - June 23, 2025 - In the evolving landscape of gene therapy, small interfering RNA (siRNA) is an important tool to achieve specific gene silencing. Based on the RNA interference (RNAi) technology, siRNA provides specific regulation of gene expression and has tremendous potential for therapeutic use in disease treatment and drug discovery. Creative Biolabs provides a variety of services that are optimized to make the best of siRNA synthesis, screening, and delivery, and a series of siRNA products with which researchers can best explore the secret of siRNAs.
"The secret to getting siRNA-based therapies to work is all about custom synthesis—basically coming up with siRNA sequences that target specific genes with laser-like precision. Creative Biolabs offers custom siRNA synthesis to assist researchers in developing sequences that have maximum gene knockdown with minimal side effects," a researcher at Creative Biolabs said.
Highlights of siRNA Synthesis Services
* Wide-ranging options for siRNA manufacture, including various backbone and base substitutions, fluorescent labels, and purification protocols.
* High-level quality control (QC) methods, including HPLC and MS confirmation.
* siRNA products provide genome-wide coverage against humans, mice, rats, and other species.
"Another big hurdle for siRNA therapy is getting it to actually get into the right cells effectively. Enter antibody-siRNA conjugates, or ARCs—what they do is bring together the specificity of antibodies with siRNA's gene-silencing capability. Together, this increases targeted delivery so that siRNA can target its intended goal while avoiding unwanted exposure," explained the researcher.
With RNA therapeutics like ARCs holding enormous prospects, Creative Biolabs continues to strive to develop diverse ARC systems, committed to providing good-quality ARC synthesis services to customers across the globe.
To enhance the efficacy of siRNA therapeutics, Creative Biolabs provides an siRNA in vitro screening service for researchers to screen gene silencing efficiency in various conditions. By employing high-throughput screening methods, researchers have the ability to screen the most effective siRNA candidates and reduce drug discovery and therapeutic development processes.
"Our scientists employ colorimetric, fluorescent, or luminescent readouts for arrayed screening and fluorescence-activated cell sorting (FACS) or next-generation sequencing (NGS) for pooled screening, providing precise and complete analysis," adds the scientist.
For further information on siRNA products and services at Creative Biolabs, visit https://www.creative-biolabs.com/gene-therapy.
About Creative Biolabs
Creative Biolabs is a renowned siRNA research company with a comprehensive portfolio of products and services that can assist in propelling your program and reducing the overall development timeline. They will share their experiences and strategies for gene therapy development at the 5th Oligonucleotides for CNS Summit, where their scientists will delve into the recent advances in siRNA therapeutics and gene therapy.
Media Contact
Company Name: Creative Biolabs
Contact Person: Candy Swift
Email: Send Email
Phone: 1-631-830-6441
Country: United States
Website: https://www.creative-biolabs.com/gene-therapy
