PAGE 1
000 B000000 10/31/2012
000 C000000 0001314966
000 D000000 N
000 E000000 NF
000 F000000 Y
000 G000000 N
000 H000000 N
000 I000000 6.1
000 J000000 A
001 A000000 BLACKROCK HEALTH SCIENCES TRUST
001 B000000 811-21702
001 C000000 8884417762
002 A000000 100 BELLEVUE PARKWAY
002 B000000 WILMINGTON
002 C000000 DE
002 D010000 19809
003 000000 N
004 000000 N
005 000000 N
006 000000 N
007 A000000 N
007 B000000 0
007 C010100 1
008 A000001 BLACKROCK ADVISORS, LLC
008 B000001 A
008 C000001 801-47710
008 D010001 WILMINGTON
008 D020001 DE
008 D030001 19809
012 A000001 BNY MELLON SHAREOWNER SERVICES
012 B000001 85-0000000
012 C010001 JERSEY CITY
012 C020001 NJ
012 C030001 07310
013 A000001 DELOITTE & TOUCHE LLP
013 B010001 PHILADELPHIA
013 B020001 PA
013 B030001 19103
014 A000001 BLACKROCK CAPITAL MARKETS, LLC
014 B000001 8-67827
014 A000002 BLACKROCK EXECUTION SERVICES
014 B000002 8-00000
014 A000003 BLACKROCK INVESTMENTS, LLC
014 B000003 8-48436
014 A000004 HARRIS WILLIAMS LLC
014 B000004 8-53380
014 A000005 PNC CAPITAL MARKETS, INC.
014 B000005 8-032493
014 A000006 PNC INVESTMENTS LLC
014 B000006 8-066195
015 A000001 THE BANK OF NEW YORK MELLON
PAGE 2
015 B000001 C
015 C010001 NEW YORK
015 C020001 NY
015 C030001 10286
015 E010001 X
018 000000 Y
019 A000000 Y
019 B000000 288
019 C000000 BLKRKADVSR
020 A000001 CREDIT SUISSE FIRST BOSTON
020 B000001 13-5659485
020 C000001 95
020 A000002 MORGAN STANLEY
020 B000002 13-2655998
020 C000002 75
020 A000003 GOLDMAN SACHS GROUP, INC.
020 B000003 13-5108880
020 C000003 71
020 A000004 JEFFERIES & CO., INC.
020 B000004 95-2622900
020 C000004 55
020 A000005 UBS FINANCIAL SERVICES INC.
020 B000005 13-2638166
020 C000005 55
020 A000006 BANC OF AMERICA SECURITIES LLC
020 B000006 56-2058405
020 C000006 52
020 A000007 DEUTSCHE BANK SECURITIES, INC.
020 B000007 13-2827803
020 C000007 41
020 A000008 CITIGROUP GLOBAL MARKETS ASIA, LTD.
020 B000008 13-2919773
020 C000008 39
020 A000009 BARCLAYS CAPITAL INC.
020 B000009 13-3297824
020 C000009 22
020 A000010 RBC DOMINION SECURITIES, INC.
020 C000010 16
021 000000 645
022 A000001 UBS SECURITIES
022 B000001 13-2932996
022 C000001 30192
022 D000001 114744
022 A000002 CREDIT SUISSE FIRST BOSTON
022 B000002 13-5659485
022 C000002 74252
022 D000002 57971
022 A000003 GOLDMAN SACHS & CO.
022 B000003 13-5108880
022 C000003 47971
022 D000003 48621
PAGE 3
022 A000004 MORGAN STANLEY
022 B000004 13-2655998
022 C000004 39316
022 D000004 21395
022 A000005 BANK OF AMERICA SECURITIES LLC
022 B000005 56-2058405
022 C000005 24698
022 D000005 31497
022 A000006 BARCLAYS CAPITAL, INC.
022 B000006 06-1031656
022 C000006 38203
022 D000006 7291
022 A000007 CITIGROUP
022 B000007 11-2418191
022 C000007 34416
022 D000007 5108
022 A000008 DEUTSCHE BANK SECURITIES INC.
022 B000008 13-2730828
022 C000008 19361
022 D000008 17513
022 A000009 RBC CAPITAL MARKETS CORP.
022 B000009 13-5033225
022 C000009 23132
022 D000009 8527
022 A000010 LIQUIDNET, INC.
022 B000010 13-4095933
022 C000010 13388
022 D000010 15011
023 C000000 428759
023 D000000 386617
024 000000 N
026 A000000 N
026 B000000 Y
026 C000000 N
026 D000000 Y
026 E000000 N
026 F000000 N
026 G010000 N
026 G020000 N
026 H000000 N
027 000000 N
028 A010000 0
028 A020000 0
028 A030000 0
028 A040000 0
028 B010000 0
028 B020000 0
028 B030000 0
028 B040000 0
028 C010000 0
028 C020000 0
PAGE 4
028 C030000 0
028 C040000 0
028 D010000 0
028 D020000 0
028 D030000 0
028 D040000 0
028 E010000 0
028 E020000 0
028 E030000 0
028 E040000 0
028 F010000 0
028 F020000 0
028 F030000 0
028 F040000 0
028 G010000 0
028 G020000 0
028 G030000 0
028 G040000 0
028 H000000 0
030 A000000 0
030 B000000 0.00
030 C000000 0.00
031 A000000 0
031 B000000 0
032 000000 0
033 000000 0
035 000000 0
036 B000000 0
038 000000 0
042 A000000 0
042 B000000 0
042 C000000 0
042 D000000 0
042 E000000 0
042 F000000 0
042 G000000 0
042 H000000 0
043 000000 0
044 000000 0
045 000000 Y
046 000000 N
047 000000 Y
048 000000 1.000
048 A010000 0
048 A020000 0.000
048 B010000 0
048 B020000 0.000
048 C010000 0
048 C020000 0.000
048 D010000 0
048 D020000 0.000
PAGE 5
048 E010000 0
048 E020000 0.000
048 F010000 0
048 F020000 0.000
048 G010000 0
048 G020000 0.000
048 H010000 0
048 H020000 0.000
048 I010000 0
048 I020000 0.000
048 J010000 0
048 J020000 0.000
048 K010000 0
048 K020000 0.000
049 000000 N
050 000000 N
051 000000 N
052 000000 N
053 A000000 Y
053 B000000 Y
053 C000000 N
054 A000000 Y
054 B000000 Y
054 C000000 Y
054 D000000 N
054 E000000 N
054 F000000 N
054 G000000 N
054 H000000 Y
054 I000000 N
054 J000000 Y
054 K000000 N
054 L000000 Y
054 M000000 N
054 N000000 N
054 O000000 Y
055 A000000 N
055 B000000 N
056 000000 Y
057 000000 N
058 A000000 N
059 000000 Y
060 A000000 N
060 B000000 N
061 000000 0
062 A000000 N
062 B000000 0.0
062 C000000 0.0
062 D000000 0.0
062 E000000 0.0
062 F000000 0.0
PAGE 6
062 G000000 0.0
062 H000000 0.0
062 I000000 0.0
062 J000000 0.0
062 K000000 0.0
062 L000000 0.0
062 M000000 0.0
062 N000000 0.0
062 O000000 0.0
062 P000000 0.0
062 Q000000 0.0
062 R000000 0.0
063 A000000 0
063 B000000 0.0
066 A000000 Y
066 B000000 N
066 C000000 N
066 D000000 N
066 E000000 Y
066 F000000 N
066 G000000 N
067 000000 N
068 A000000 N
068 B000000 N
069 000000 N
070 A010000 Y
070 A020000 N
070 B010000 Y
070 B020000 Y
070 C010000 Y
070 C020000 N
070 D010000 Y
070 D020000 N
070 E010000 Y
070 E020000 N
070 F010000 Y
070 F020000 N
070 G010000 Y
070 G020000 N
070 H010000 Y
070 H020000 N
070 I010000 N
070 I020000 N
070 J010000 Y
070 J020000 N
070 K010000 Y
070 K020000 Y
070 L010000 Y
070 L020000 Y
070 M010000 Y
070 M020000 Y
PAGE 7
070 N010000 Y
070 N020000 Y
070 O010000 Y
070 O020000 N
070 P010000 Y
070 P020000 Y
070 Q010000 N
070 Q020000 N
070 R010000 N
070 R020000 N
071 A000000 433566
071 B000000 418709
071 C000000 199869
071 D000000 209
072 A000000 12
072 B000000 0
072 C000000 2954
072 D000000 0
072 E000000 19
072 F000000 2092
072 G000000 0
072 H000000 0
072 I000000 27
072 J000000 98
072 K000000 0
072 L000000 25
072 M000000 19
072 N000000 9
072 O000000 0
072 P000000 0
072 Q000000 0
072 R000000 47
072 S000000 25
072 T000000 0
072 U000000 0
072 V000000 0
072 W000000 25
072 X000000 2367
072 Y000000 8
072 Z000000 614
072AA000000 35743
072BB000000 18298
072CC010000 14085
072CC020000 0
072DD010000 624
072DD020000 0
072EE000000 18502
073 A010000 0.0900
073 A020000 0.0000
073 B000000 2.4100
073 C000000 0.0000
PAGE 8
074 A000000 2
074 B000000 0
074 C000000 0
074 D000000 0
074 E000000 0
074 F000000 216968
074 G000000 0
074 H000000 0
074 I000000 8211
074 J000000 1933
074 K000000 2
074 L000000 236
074 M000000 10
074 N000000 227362
074 O000000 1456
074 P000000 206
074 Q000000 0
074 R010000 0
074 R020000 0
074 R030000 2999
074 R040000 4324
074 S000000 0
074 T000000 218377
074 U010000 7706
074 U020000 0
074 V010000 28.34
074 V020000 0.00
074 W000000 0.0000
074 X000000 13715
074 Y000000 4062
075 A000000 0
075 B000000 209528
076 000000 27.86
077 A000000 Y
077 B000000 Y
077 C000000 N
077 D000000 N
077 E000000 N
077 F000000 N
077 G000000 N
077 H000000 N
077 I000000 N
077 J000000 N
077 K000000 N
077 L000000 N
077 M000000 N
077 N000000 N
077 O000000 N
077 P000000 N
077 Q010000 N
077 Q020000 N
PAGE 9
077 Q030000 N
078 000000 N
080 A000000 Federal Insurance Company
080 B000000 National Union Fire Insurance Company
080 C000000 69325
081 A000000 Y
081 B000000 92
082 A000000 N
082 B000000 0
083 A000000 N
083 B000000 0
084 A000000 N
084 B000000 0
085 A000000 Y
085 B000000 N
086 A010000 100
086 A020000 2684
086 B010000 0
086 B020000 0
086 C010000 0
086 C020000 0
086 D010000 0
086 D020000 0
086 E010000 0
086 E020000 0
086 F010000 0
086 F020000 0
087 A010000 COMMON
087 A020000 09250W107
087 A030000 BME
088 A000000 N
088 B000000 N
088 C000000 N
088 D000000 N
SIGNATURE BOB MAURER
TITLE MANAGER