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                                  UNITED STATES
                       SECURITIES AND EXCHANGE COMMISSION
                             Washington, D.C. 20549

                                  SCHEDULE 13G

                    Under the Securities Exchange Act of 1934
                          (Amendment No.____________)*

                         United Therapeutics Corporation
--------------------------------------------------------------------------------
                                (Name of Issuer)

                                  Common Stock
--------------------------------------------------------------------------------
                         (Title of Class of Securities)

                                    91307C102
--------------------------------------------------------------------------------
                                 (CUSIP Number)

                                October 10, 2006
--------------------------------------------------------------------------------
             (Date of Event Which Requires Filing of this Statement)

Check the appropriate box to designate the rule pursuant to which this Schedule
is filed:

          [x]  Rule 13d-1(b)

          [_]  Rule 13d-1(c)

          [_]  Rule 13d-1(d)

* The remainder of this cover page shall be filled out for a reporting person's
initial filing on this form with respect to the subject class of securities, and
for any subsequent amendment containing information which would alter the
disclosures provided in a prior cover page.

The information required in the remainder of this cover page shall not be deemed
to be "filed" for the purpose of Section 18 of the Securities Exchange Act of
1934 ("Act") or otherwise subject to the liabilities of that section of the Act
but shall be subject to all other provisions of the Act (however, see the
Notes).

PERSONS WHO RESPOND TO THE COLLECTION OF INFORMATION CONTAINED IN THIS FORM ARE
NOT REQUIRED TO RESPOND UNLESS THE FORM DISPLAYS A CURRENTLY VALID OMB CONTROL
NUMBER.



CUSIP No.   91307C102
--------------------------------------------------------------------------------

1.    NAMES OF REPORTING PERSONS
      I.R.S. IDENTIFICATION NOS. OF ABOVE PERSONS (ENTITIES ONLY)
Fred Alger Management, Inc. 13-2510833

2.    CHECK THE APPROPRIATE BOX IF A MEMBER OF A GROUP (SEE INSTRUCTIONS)
         (a)  [ ]
         (b)  [ ]

3.    SEC USE ONLY

4.    CITIZENSHIP OR PLACE OF ORGANIZATION
New York, New York

  NUMBER OF    5.   SOLE VOTING POWER
   SHARES           1,504,000
BENEFICIALLY   6.   SHARED VOTING POWER
  OWNED BY          -0-
    EACH       7.   SOLE DISPOSITIVE POWER
  REPORTING         1,504,000
   PERSON      8.   SHARED DISPOSITIVE POWER
    WITH:           -0-

9.    AGGREGATE AMOUNT BENEFICIALLY OWNED BY EACH REPORTING PERSON 1,504,000

10.   CHECK IF THE AGGREGATE AMOUNT IN ROW (9) EXCLUDES CERTAIN SHARES (SEE
      INSTRUCTIONS)
      [_]

11.   PERCENT OF CLASS REPRESENTED BY AMOUNT IN ROW 9
        6.56%

12.  TYPE OF REPORTING PERSON (SEE INSTRUCTIONS)
        Fred Alger Management, Inc. IA



CUSIP No. 91307C102
Item 1(a).  Name of Issuer:
United Therapeutics Corporation

Item 1(b).  Address of Issuer's Principal Executive Offices:
1110 Spring Street
Silver Spring, MD 20910

Item 2(a).  Name of Person Filing:
Fred Alger Management, Inc.*

Item 2(b).  Address of Principal Business Office, or if None, Residence:
111 Fifth Avenue, New York, NY 10003

Item 2(c).  Citizenship:
New York

Item 2(d).  Title of Class of Securities:
Common Stock

Item 2(e).  CUSIP Number:
91307C102

Item 3. If This Statement is Filed Pursuant to Rule 13d-1(b), or 13d-2(b) or
(c), Check Whether the Person Filing is a:

     (a)     [_] Broker or dealer registered under Section 15 of the Act (15
             U.S.C. 78o).

     (b)     [_] Bank as defined in Section 3(a)(6) of the Act (15 U.S.C. 78o).

     (c)     [_] Insurance company as defined in Section 3(a)(19) of the Act (15
             U.S.C. 78o).

     (d)     [_] Investment company registered under Section 8 of the Investment
             Company Act of 1940 (15 U.S.C. 80a-8).

     (e)     [x] An investment adviser in accordance with
             s240.13d-1(b)(1)(ii)(E);

     (f)     [_] An employee benefit plan or endowment fund in accordance with
             s240.13d-1(b)(1)(ii)(F);

     (g)     [_] A parent holding company or control person in accordance with
             s240.13d-1(b)(1)(ii)(G);

     (h)     [_] A savings association as defined in Section 3(b) of the Federal
             Deposit Insurance Act (12 U.S.C. 1813);

     (i)     [_] A church plan that is excluded from the definition of an
             investment company under Section 3(c)(14) of the Investment Company
             Act of 1940 (15 U.S.C. 80a-3);

     (j)     [_] Group, in accordance with s240.13d-1(b)(1)(ii)(J).

* By virtue of the Alger family's ownership of a controlling interest in Alger
Associates, which indirectly owns Fred Alger Management, Inc., ownership of the
shares may be imputed to the Alger Family.



CUSIP No. 91307C102

Item 4.  Ownership.

     Provide the following information regarding the aggregate number and
percentage of the class of securities of the issuer identified in Item 1.

     (a) Amount beneficially owned:
         1,504,000

     (b) Percent of class:
         6.56%

     (c) Number of shares as to which such person has:

            (i) Sole power to vote or to direct the vote
                       1,504,000

            (ii) Shared power to vote or to direct the vote
                       -0-

            (iii) Sole power to dispose or to direct the disposition of
                       1,504,000

            (iv) Shared power to dispose or to direct the disposition of

                       -0-

Item 5.  Ownership of Five Percent or Less of a Class.

     If this statement is being filed to report the fact that as of the date
hereof the reporting person has ceased to be the beneficial owner of more than
five percent of the class of securities check the following [ ].

Item 6.  Ownership of More Than Five Percent on Behalf of Another Person.
         n/a

Item 7.  Identification and Classification of the Subsidiary Which Acquired the
         Security Being Reported on by the Parent Holding Company. n/a

Item 8.  Identification and Classification of Members of the Group.
         n/a

Item 9.  Notice of Dissolution of Group.
         n/a

Item 10. Certification.

     (a) The following certification shall be included if the statement is filed
pursuant to s240.13d-1(b):

        By signing below I certify that, to the best of my knowledge and belief,
the securities referred to above were acquired and are held



in the ordinary course of business and were not acquired and not held for the
purpose of or with the effect of changing or influencing the control of the
issuer of the securities and were not acquired and are not held in connection
with or as a participant in any transaction having that purpose or effect.

            After reasonable inquiry and to the best of my knowledge and belief,
I certify that the information set forth in this statement is true, complete and
correct.

                                             FRED ALGER MANAGEMENT, INC.

                                             By: /s/ Hal Liebes
                                             Executive Vice President
                                             October 10, 2006

The original statement shall be signed by each person on whose behalf the
statement is filed or his authorized representative. If the statement is signed
on behalf of a person by his authorized representative other than an executive
officer or general partner of the filing person, evidence of the
representative's authority to sign on behalf of such person shall be filed with
the statement, provided, however, that a power of attorney for this purpose
which is already on file with the Commission may be incorporated by reference.
The name and any title of each person who signs the statement shall be typed or
printed beneath his signature.

Note: Schedules filed in paper format shall include a signed original and five
copies of the schedule, including all exhibits. See s240.13d-7 for other parties
for whom copies are to be sent.

ATTENTION. INTENTIONAL MISSTATEMENTS OR OMISSIONS OF FACT CONSTITUTE FEDERAL
CRIMINAL VIOLATIONS (SEE 18 U.S.C. 1001).