FORM 5 Check this box if no longer subject to Section 16. Form 4 or Form 5 obligations may continue. See Instruction 1(b). Form 3 Holdings Reported Form 4 Transactions Reported

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 ANNUAL STATEMENT OF CHANGES IN BENEFICIAL OWNERSHIP OF SECURITIES Filed pursuant to Section 16(a) of the Securities Exchange Act of 1934, Section 17(a) of the Public Utility Holding Company Act of 1935 or Section 30(h) of the Investment Company Act of 1940

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1. Name and Address of Reporting Person * Frist William R 2. Issuer Name and Ticker or Trading Symbol HCA Holdings, Inc. [(NONE)] 5. Relationship of Reporting Person(s) to Issuer (Check all applicable) _____ Director __X__ 10% Owner _____ Officer (give title below) _____ Other (specify below) (Last) (First) (Middle) 3100 WEST END AVENUE 3. Statement for Issuer's Fiscal Year Ended (Month/Day/Year) 12/31/2010 (Street) NASHVILLE, TN 37203 4. If Amendment, Date Original Filed(Month/Day/Year) 6. Individual or Joint/Group Reporting (check applicable line) _X_ Form Filed by One Reporting Person ___ Form Filed by More than One Reporting Person (City) (State) (Zip) Table I - Non-Derivative Securities Acquired, Disposed of, or Beneficially Owned

1.Title of Security (Instr. 3) 2. Transaction Date (Month/Day/Year) 2A. Deemed Execution Date, if any (Month/Day/Year) 3. Transaction Code (Instr. 8) 4. Securities Acquired (A) or Disposed of (D) (Instr. 3, 4 and 5) 5. Amount of Securities Beneficially Owned at end of Issuer's Fiscal Year (Instr. 3 and 4) 6. Ownership Form: Direct (D) or Indirect (I) (Instr. 4) 7. Nature of Indirect Beneficial Ownership (Instr. 4) Amount (A) or (D) Price Common Stock, par value $0.01 per share 01/26/2010   G 295 A $ 0 1,451,097 I Held indirectly through Hercules Holding II, LLC by The William R. Frist 2010 Family GRAT Trust (1) (2) (3) Common Stock, par value $0.01 per share 01/26/2010   G 1,180 A $ 0 17,269 I Held indirectly through Hercules Holding II, LLC by spouse and children (1) (2) Common Stock, par value $0.01 per share 04/30/2010   G 55,810 A $ 0 55,810 I Held indirectly through Hercules Holding II, LLC by The William Frist 2010 GRAT Trust (1) (3) Common Stock, par value $0.01 per share     3         I Held indirectly through Hercules Holding II, LLC by the William R. Frist Family Partnership (1) (3) Common Stock, par value $0.01 per share     3         I Held indirectly through Hercules Holding II, LLC by Frisco Inc. (1) (4) Common Stock, par value $0.01 per share     3         I Held indirectly through Hercules Holding II, LLC by Frisco Partners (1) (4)

Reminder: Report on a separate line for each class of securities beneficially owned directly or indirectly.

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SEC 2270 (9-02)

Table II - Derivative Securities Acquired, Disposed of, or Beneficially Owned
(e.g., puts, calls, warrants, options, convertible securities)

1. Title of Derivative Security (Instr. 3)

2. Conversion or Exercise Price of Derivative Security

3. Transaction Date (Month/Day/Year)

3A. Deemed Execution Date, if any (Month/Day/Year)

4. Transaction Code (Instr. 8)

5. Number of Derivative Securities Acquired (A) or Disposed of (D) (Instr. 3, 4, and 5)

6. Date Exercisable and Expiration Date (Month/Day/Year)

7. Title and Amount of Underlying Securities (Instr. 3 and 4)

8. Price of Derivative Security (Instr. 5)

9. Number of Derivative Securities Beneficially Owned at End of Issuer's Fiscal Year (Instr. 4)

10. Ownership Form of Derivative Security: Direct (D) or Indirect (I) (Instr. 4)

11. Nature of Indirect Beneficial Ownership (Instr. 4)

(A)

(D)

Date Exercisable

Expiration Date

Title

Amount or Number of Shares

Reporting Owners

Reporting Owner Name / Address	Relationships
	Director	10% Owner	Officer	Other
Frist William R 3100 WEST END AVENUE NASHVILLE, TN 37203	Â	  X	Â	Â

Signatures

/s/ Natalie H. Cline, Attorney-in-Fact for Reporting Person		02/14/2011
**Signature of Reporting Person		Date

Explanation of Responses:

*	If the form is filed by more than one reporting person, see Instruction 4(b)(v).
**	Intentional misstatements or omissions of facts constitute Federal Criminal Violations. See 18 U.S.C. 1001 and 15 U.S.C. 78ff(a).
(1)	Hercules Holding II, LLC ("Hercules") holds 91,845,692 shares of the common stock of HCA Holdings, Inc. Hercules has issued one unit per share of HCA Holdings, Inc. that it owns directly. Hercules is held by a private investor group, including affiliates of Bain Capital Investors, LLC, Kohlberg Kravis Roberts & Co. L.P. and Merrill Lynch Global Private Equity, and affiliates of HCA Inc. founder Dr. Thomas F. Frist, Jr. The Reporting Person may be deemed to be a member of a group exercising voting and investment control over the shares of common stock of HCA Holdings, Inc. held by Hercules. However, the Reporting Person disclaims membership in any such group and disclaims beneficial ownership of these securities, except to the extent of his pecuniary interest therein.
(2)	William R. Frist received gifts of 295 and 55,810 units of Hercules on January 26, 2010 and April 30, 2010, respectively. The 295 units were subsequently transferred to The William R. Frist 2010 Family GRAT Trust and the 55,810 units were subsequently transferred to The William Frist 2010 GRAT Trust. Mr. Frist may be deemed to have indirect beneficial ownership in respect of 17,269 units of Hercules through an indirect pecuniary interest in such units held by his children and his wife, and therefore may be deemed to own indirectly the same number of shares of common stock of the Issuer.
(3)	Mr. Frist may be deemed the beneficial owner of the 268,259 units of Hercules Holding II, LLC held by the William R. Frist Family Partnership, of which his wife serves as trustee, the 55,810 units of Hercules held by The William Frist 2010 GRAT Trust, of which he serves as trustee, and the 1,451,097 units of Hercules held by The William R. Frist 2010 Family GRAT Trust, of which he serves as trustee, and therefore may be deemed to own indirectly the same number of shares of common stock of the Issuer.
(4)	Mr. Frist may also be deemed to share voting and dispositive power with respect to 17,804,125 shares of the Issuer beneficially owned by Frisco Inc., by virtue of his position as a director of Frisco Inc. and with respect to 17,804,125 shares of the Issuer beneficially owned by Frisco Partners, by virtue of his position as a partner of Frisco Partners. Frisco Inc. and Frisco Partners each have beneficial ownership of 17,804,125 units of Hercules, and therefore may be deemed to own indirectly the same number of shares of common stock of the Issuer.
  Remarks: On November 22, 2010, HCA Holdings, Inc. became the successor of HCA Inc. pursuant to a merger. The merger resulted in HCA Holdings, Inc. becoming a parent holding company of HCA Inc., but did not alter the proportionate interests of security holders.

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