FORM 4 Check this box if no longer subject to Section 16. Form 4 or Form 5 obligations may continue. See Instruction 1(b).

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 STATEMENT OF CHANGES IN BENEFICIAL OWNERSHIP OF SECURITIES Filed pursuant to Section 16(a) of the Securities Exchange Act of 1934, Section 17(a) of the Public Utility Holding Company Act of 1935 or Section 30(h) of the Investment Company Act of 1940

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(Print or Type Responses)

1. Name and Address of Reporting Person * TAMERIUS JOHN   2. Issuer Name and Ticker or Trading Symbol QUIDEL CORP /DE/ [QDEL] 5. Relationship of Reporting Person(s) to Issuer (Check all applicable) _____ Director _____ 10% Owner __X__ Officer (give title below) _____ Other (specify below) SVP - Clinical/Reg Affairs (Last) (First) (Middle) 10165 MCKELLAR COURT 3. Date of Earliest Transaction (Month/Day/Year) 09/27/2010 (Street) SAN DIEGO, CA 92121 4. If Amendment, Date Original Filed(Month/Day/Year) 6. Individual or Joint/Group Filing(Check Applicable Line) _X_ Form filed by One Reporting Person ___ Form filed by More than One Reporting Person (City) (State) (Zip) Table I - Non-Derivative Securities Acquired, Disposed of, or Beneficially Owned

1.Title of Security (Instr. 3) 2. Transaction Date (Month/Day/Year) 2A. Deemed Execution Date, if any (Month/Day/Year) 3. Transaction Code (Instr. 8) 4. Securities Acquired (A) or Disposed of (D) (Instr. 3, 4 and 5) 5. Amount of Securities Beneficially Owned Following Reported Transaction(s) (Instr. 3 and 4) 6. Ownership Form: Direct (D) or Indirect (I) (Instr. 4) 7. Nature of Indirect Beneficial Ownership (Instr. 4) Code V Amount (A) or (D) Price Common Stock 01/03/2011   M   70 (1) A (1) 38,033 D

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Table II - Derivative Securities Acquired, Disposed of, or Beneficially Owned
(e.g., puts, calls, warrants, options, convertible securities)

1. Title of Derivative Security (Instr. 3)

2. Conversion or Exercise Price of Derivative Security

3. Transaction Date (Month/Day/Year)

3A. Deemed Execution Date, if any (Month/Day/Year)

4. Transaction Code (Instr. 8)

5. Number of Derivative Securities Acquired (A) or Disposed of (D) (Instr. 3, 4, and 5)

6. Date Exercisable and Expiration Date (Month/Day/Year)

7. Title and Amount of Underlying Securities (Instr. 3 and 4)

8. Price of Derivative Security (Instr. 5)

9. Number of Derivative Securities Beneficially Owned Following Reported Transaction(s) (Instr. 4)

10. Ownership Form of Derivative Security: Direct (D) or Indirect (I) (Instr. 4)

11. Nature of Indirect Beneficial Ownership (Instr. 4)

Code

V

(A)

(D)

Date Exercisable

Expiration Date

Title

Amount or Number of Shares

Restricted Stock Unit

(2)

09/27/2010

A(2)

1 (2)

(2)

(2)

Common Stock

(2)

$ 0

1 (2)

D

Restricted Stock Unit

(2)

01/03/2011

M(2)

1 (2)

(2)

(2)

Common Stock

(2)

$ 0

0 (2)

D

Reporting Owners

Reporting Owner Name / Address	Relationships
	Director	10% Owner	Officer	Other
TAMERIUS JOHN 10165 MCKELLAR COURT SAN DIEGO, CA 92121			SVP - Clinical/Reg Affairs

Signatures

Robert J. Bujarski, attorney-in-fact for John Tamerius		01/05/2011
**Signature of Reporting Person		Date

Explanation of Responses:

*	If the form is filed by more than one reporting person, see Instruction 4(b)(v).
**	Intentional misstatements or omissions of facts constitute Federal Criminal Violations. See 18 U.S.C. 1001 and 15 U.S.C. 78ff(a).
(1)	As described in footnote (2) below, the common shares were received pursuant to a specified formula upon vesting of a restricted stock unit (the "RSU") granted under the Company's Q4 2010 Employee Deferred Compensation Program (the "Program") and 2010 Equity Incentive Plan.
(2)	The RSU was granted pursuant to the Program. Under the Program, the Reporting Person received the RSU, which vested on January 3, 2011, upon an election to defer a percentage of his base salary applicable to the period from September 27, 2010 through December 31, 2010 (the "Covered Period"). Upon vesting of the RSU, the Reporting Person was entitled to receive common shares equal to (i) the amount of his salary deferred under the Program divided by the average of the market closing prices for the common shares over the Covered Period, and (ii) then multiplying the result of the foregoing by 1.2. Pursuant to this formula, the Reporting Person received 70 common shares upon vesting of the RSU.

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