As filed with the Securities and Exchange Commission on April 30, 2009
 
Registration No. 333-110858
 
SECURITIES AND EXCHANGE COMMISSION

WASHINGTON, D.C. 20549
——————————
POST-EFFECTIVE AMENDMENT NO. 5 TO

FORM S-1

REGISTRATION STATEMENT
UNDER
THE SECURITIES ACT OF 1933
——————————
NEOPROBE CORPORATION

(Exact name of registrant as specified in its charter)

Delaware
2835
31-1080091
(State or other jurisdiction of
incorporation or organization)
(Primary standard industrial
Classification number)
(IRS employer
identification number)
——————————
425 Metro Place North, Suite 300
Dublin, Ohio 43017-1367
(614) 793-7500
(Address and telephone number of principal executive offices)
——————————
425 Metro Place North, Suite 300
Dublin, Ohio 43017-1367
(Address of principal place of business)
——————————
Brent L. Larson, Vice President, Finance and Chief Financial Officer
Neoprobe Corporation
425 Metro Place North, Suite 300
Dublin, Ohio 43017-1367
(614) 793-7500
(Name, address and telephone number of agent for service)
——————————
Copies to:
 
William J. Kelly, Jr., Esq.
Porter, Wright, Morris & Arthur LLP
41 South High Street
Columbus, Ohio 43215
Telephone No. (614) 227-2136
wjkelly@porterwright.com
 
Approximate date of commencement of proposed sale to the public:  Not Applicable

 
 

 

If any of the securities being registered on this Form are to be offered on a delayed or continuous basis pursuant to Rule 415 under the Securities Act, check the following box. o

If this form is filed to register additional securities for an offering pursuant to Rule 462(b) under the Securities Act, please check the following box and list the Securities Act registration statement number of the earlier effective registration statement for the same offering. o

If this form is a post-effective amendment filed pursuant to Rule 462(c) under the Securities Act, check the following box and list the Securities Act registration statement number of the earlier effective registration statement for the same offering. o

If this form is a post-effective amendment filed pursuant to Rule 462(d) under the Securities Act, check the following box and list the Securities Act registration statement number of the earlier effective registration statement for the same offering. o

Indicate by check mark whether the registrant is a large accelerated filer, a non-accelerated filer, or a smaller reporting company.  See the definitions of “large accelerated filer” and “smaller reporting company” in Rule 12b-2 of the Exchange Act.

Large accelerated filer o                                                                           Accelerated filer o
Non-accelerated filer   o                                                                           Smaller reporting company x
  (Do not check if a smaller reporting company)


EXPLANATORY NOTE

Deregistration of Securities

We originally registered 21,817,257 shares of our common stock pursuant to a Registration Statement on Form SB-2 (File No. 333-110858) filed with the Securities and Exchange Commission (the “SEC”) on December 2, 2003, as most recently amended on Form S-1 May 5, 2008, and subsequently declared effective by the SEC on May 8, 2008 (the “Registration Statement”). The Registration Statement related to the sale of shares of our common stock by various persons named therein as “selling stockholders,” who purchased shares of our common stock through the conversion of debt or the exercise of warrants.

We have filed this Post-effective Amendment No. 5 to the Registration Statement solely for the purpose of fulfilling the Company’s obligation under Item 512(a)(3) of Regulation S-K promulgated under the Securities Act of 1933, as amended (“Item 512”), which requires that the Company remove from registration by means of a post-effective amendment any of the securities originally registered by the Registration Statement that remained unsold at the termination of the offering. The offering related to the Registration Statement terminated on April 30, 2009. Pursuant to this Post-effective Amendment No. 5 to the Registration Statement, we are seeking to deregister 1,023,350 shares of our common stock that were registered pursuant to the Registration Statement and not sold prior to the termination of the offering. Therefore, in accordance with our undertaking contained in Part II of the Registration Statement, we hereby respectfully request that the Securities and Exchange Commission remove from registration those shares of common stock that were registered pursuant to the Registration Statement and remain unsold thereunder. The Registration Statement is hereby amended, as appropriate, to reflect the deregistration of such shares.


 
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Item 27.     Exhibits.                                                 

 
Exhibit
Number
  Exhibit Description
       
 
24
*
Powers of Attorney (incorporated by reference to the Company’s Registration Statement on Form SB-2 filed with the SEC December 2, 2003 (Registration No. 110858), with the exception of the Powers of Attorney for Mr. Aschinger, and Drs. Bland and Johnson, which were filed as Exhibit 24.1 to Post-effective Amendment No. 3 to the Company’s Registration Statement on Form SB-2 filed with the SEC September 20, 2007, and the Power of Attorney for Mr. Troup, which is filed herewith).
 
____________
 
*Filed herewith
 
 
 
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Signatures

In accordance with the requirements of the Securities Act of 1933, as amended, the registrant certifies that it has reasonable grounds to believe that it meets all of the requirements of filing on Form S-1 and has authorized this Post-effective Amendment No. 5 to its Registration Statement to be signed on its behalf by the undersigned in the City of Dublin, Ohio, on April 30, 2009.
 
  Neoprobe Corporation  
       
 
By:
/s/ Brent L. Larson  
    Brent L. Larson, Vice President, Finance  
    and Chief Financial Officer  
       
 
In accordance with the requirements of the Securities Act of 1933, this registration statement was signed by the following persons in the capacities and on the dates indicated:
 
Signature
 
Title
 
Date
         
/s/ David C. Bupp*
 
President, Chief Executive Officer
 
April 30, 2009
David C. Bupp
 
and Director
   
   
(principal executive officer)
   
         
/s/ Brent L. Larson
 
Vice President, Finance and Chief
 
April 30, 2009
Brent L. Larson
 
Financial Officer
   
   
(principal financial officer and
   
   
principal accounting officer)
   
         
/s/ Carl J. Aschinger, Jr.*
 
Chairman of the Board of
 
April 30, 2009
Carl J. Aschinger, Jr.
 
Directors
   
         
/s/ Reuven Avital*
 
Director
 
April 30, 2009
Reuven Avital
       
         
/s/ Kirby I. Bland*
 
Director
 
April 30, 2009
Kirby I. Bland
       
         
/s/ Owen E. Johnson*
 
Director
 
April 30, 2009
Owen E. Johnson
       
         
/s/ Fred B. Miller*
 
Director
 
April 30, 2009
Fred B. Miller
       
         
/s/ Gordon A. Troup*
 
Director
 
April 30, 2009
Gordon A. Troup
       
         
/s/ J. Frank Whitley, Jr.*
 
Director
 
April 30, 2009
J. Frank Whitley, Jr.
       
         
*By: /s/ Brent L. Larson
       
Brent L. Larson, Attorney-in fact
       

 
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